USU Conference Systems, International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) 2017

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Relationship Between Depression With FEV1 Percent Predicted and BODE Index in Chronic Obstructive Pulmonary Disease
Heri Gunawan

Last modified: 2017-10-13


H.Gunawan1, H.Hanum2, A.Abidin3, and W.Hanida2

1Resident of Internal Medicine Department

2Divison of Psychosomatic and 3Division of Pulmonology, Department of Internal Medicine

Faculty of Medicine, North Sumatera University, Medan, Indonesia

Adam Malik General Hospital Medan, Indonesia

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Abstract. WHO reported more than 3 million people die from COPD in 2012 and are expected to rank third after cardiovascular and cancer diseases in the future. Data in Indonesia showed the prevalence of COPD was 3.7%. Recent studies reported prevalence of depression in COPD patients was higher than in control group. So, it’s important for clinicians to understand the relationship of depression symptoms with clinical aspects of COPD.

Aim: To determine the association of depression symptoms with lung function and BODE index in patients with stable COPD.

Methods: A cross sectional study of 98 stable COPD outpatients from January to June 2017. Data were analyzed using Independent t-test, Mann Whitney test and Spearman’s rank Correlation.

Results: COPD patients with depression had higher mMRC scores and lower FEV1 percent predicted and 6-Minutes Walk Test compared to those without depression. There was a moderate strength of correlation (r = -0.43) between depression symptoms and FEV1 percent predicted, and strong correlation (r = 0.614) between depression symptoms and BODE index.

Conclusion: There’s a stronger correlation between depression symptoms and BODE index compared with correlation between depression symptoms and FEV1 percent predicted. This indicates BODE index is more accurate to describe symptoms of depression in COPD patients.

Keywords: COPD, Depression, CES-D, BODE Index