Urinary tract infection (UTI)  is a major health problem which ranks as the second leading cause of infection after respiratory tract infections. The problem of antimicrobial resistance in UTI has become a burden in the management of the disease due to high usage of antibiotics. A comprehensive understanding of the etiology and the antimicrobial resistance of the uropathogen is essential in order to provide adequate treatment. This study aims to determine the etiologic agents and their susceptibility pattern in UTI patients. The analysis was performed retrospectively on culture isolates obtained from urine samples received at the Department of Microbiology, Dr.Pirngadi General Hospital, Medan, Indonesia in the period of time from January 2015 until December 2016. Female participants of the study were found with higher prevalence of UTI in comparison with males. Enterobacter (64.58%) was the most common uropathogen found as the etiologic agent, followed by E. coli (11.46%), Citrobacter and Klebsiella (9.38% each). Amikacin and meropenem were the most sensitive antimicrobial agents for Enterobacter, E. coli, Citrobacter, and Klebsiella, showing low resistance rate.  This study showed that Enterobacter was the most dominant bacterial pathogen of UTI. Amikacin and meropenem were the antibiotics with high sensitivity for UTI treatment.

 

Keywords: Urinary tract infection, antimicrobial, culture, resistance