Abstract. Increasing rate of Diabetic Foot Infections (DFIs) caused by multi-drug-resistance pathogens plays a huge role in the duration of hospitalization, morbidity, and mortality of diabetic patients. Objective: to assess the antibiotic sensitivity pattern of bacteria in DFIs and causative microorganisms. Methods: Using cross-sectional retrospective study, data were collected from medical records of DFIs patients previously hospitalized at Haji Adam Malik Hospital, Medan from January to July 2017. 33 patients met the criteria and got enrolled in the study. The classification of DFIs was evaluated according to Wagner’s Classification. Evaluation of antibiotic sensitivity and identification of causative microorganisms were performed in standard microbiologic methods. Results: The most common grade of DFIs was Grade-4 (48,5%), followed by Grade-3 (39.4%) and Grade-5 (9.1%). A total of 12 pathogens were identified. The most common infecting microorganism isolated on pus cultures was Klebsiella pneumoniae (33.3%), followed by Escherichia coli (24.2%), Acinetobacter baumanni (12.1%), and Staphylococcus aureus (9.1%). Frequent susceptible antibiotics were Amikacin (88,8%), Imipenem (87%), Meropenem (84,6%), Erythromycin (75%), and Cefoperazone/Sulbactam (68,9%). Conclusion: DFIs are polymicrobial infections where in this study K. pneumoniae was the most common cause microorganism.

Keywords: diabetes mellitus, diabetic foot infection, antibiotic sensitivity.