Indonesia is among the country where malaria is still the lead population problem. The high rate of mortality and morbidity generally occured due to delays in diagnosis which is strongly influenced by the availability of diagnostic tools and personnel with required laboratory skill. This diagnostic study aims to compare the accuracy of Parascreen as a Rapid Diagnostic Test (RDT) without special skill requirement, to gold standard microscopic method for malaria diagnosis. The study was conducted in Sub district Lima Puluh North Sumatera Province from December 2015 to January 2016. Subject was taken cross-sectionally from a population with distinguished characteristics of people with Malaria in Sub district Lima Puluh. The result showed a sensitivity of 100% and a specificity of 72.4% with a positive predictive value of 89.9% and a negative predictive value of 100%, negative likelihood ratio is 0 and the positive likelihood ratio of 27.6 for Parascreen. This research indicates that Parascreen had a high sensitivity and specificity and may be considered as an alternative for the diagnosis of malaria in Sub district Lima Puluh North Sumatera Province especially in areas where no skilled microscopist is available.

Keyword: malaria, microscopic examination , rapid diagnostic test