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Introduction: Indonesia is the second country with the largest TB (tuberculosis) burden in the world. Building capacity and increasing universal acces for fast and accurate laboratory diagnostic are important on controlling TB in Indonesia. Improvement on controlling TB and reducing the consequences can be accelerated trough early diagnosis and correct treatment. This study used PCR test a gold standard, although it is expensive for routine diagnosis, so a fast, accurate and cheap diagnostic method such as fine needle aspiration biopsyis needed. Purpose: to determine the accuracy of fine needle aspiration biopsy cytology in making tuberculous lymphadenitis. Method: this study is analytic cross sectional based design. The amount of sample (n) is all patients who are suspected with tuberculous lymphadenitis. The fine needle aspiration biopsy test is confirmed by PCR test, then diagnostic test is done to assess the sensitivity, specificity, accuracy, positive predictive value and negative predictive value. Result: Sensitivity 92.50%, specificity 96.49%, accuracy 94.85%, positve predictive value 94.87% and negative predictive value 94.83% were obtained from diagnostic test. Fine needle aspiration biopsy is a supporting examination with high accuracy for tuberculous lymphadenitis. Conclusion: The sensitivity, specificity, positive predictive value, negative predictive value and fine needle aspiration biopsy cytology accuracy are high, so fine needle aspiration biopsy is recommended to make tuberculous lymphadenitis diagnosis. Keyword: TB, lymphadenitis, aspiration biopsy, FNAB, PCR.