Abstract. Folic acid deficiency has been identified as a risk factor for schizophrenia through epidemiology, biochemistry and gene-related studies. Compared with healthy people, schizophrenic patients may have high homocysteine plasma values and homocysteine or low levels of folic acid, which seems to correlate with extrapyramidal motor symptoms caused by neuroleptic therapy and with symptoms of schizophrenia. Aims. in this present study we focus on the difference of folic acid level between schizophrenic patient and control group. Method. The study sample consisted of schizophrenic patients and 14 people in the control group and performed blood sampling to obtain the results of folic acid levels. Result. Folic acid levels in both groups were within normal range, but the schizophrenic patient group had lower mean folic acid values of 5.00 ng/ml (sb 1.66), compared with the control group with mean folic acid values of 10.75 ng/ml (sb 4.33). Conclusion: In this study it was found that the group of schizophrenic patients had a lower value of folic acid than the control group.

Keyword: Folic acid, Schizophrenic Patient