USU Conference Systems, International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) 2017

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Insidence of Multidrug-Resistant, Extensively Drug-Resistant and Pan Drug-Resistant Bacteria in Children Hospitalized at Dr. Hasan Sadikin General Hospital Bandung Indonesia
riyadi adrizain, anggraini alam, Djatnika Setiabudi, Filla reviyani Suryaningrat

Last modified: 2017-09-14


Background: Antibiotic resistance has become global issue, with 700,000 deaths attributable to multidrug-resistance (MDR) occurring each year. Centers for Disease Control and Prevention (CDC) show rapidly increasing rates of infection due to antibiotic-resistant bacteria.

Objective: To describe the insidence of MDR, extensively drug-resistant (XDR) and pan drug-resistant (PDR) in Enterococcus spp., staphylococcus aureus, K. pneumoniae, Acinetobacter baumanii, P. aeruginosa, and Enterobacter spp. (ESKAPE) pathogens in children admitted to Dr. Hasan Sadikin Hospital

Methods: All children patient that been drawn blood culture from January 2015 to December 2016 were retrospectively studied. Data including number of drawn blood culture, number of positive results, type of bacteria, sensitivity pattern. International standard definitions for acquired resistance by ECDC and CDC was used as definitions for MDR, XDR and PDR bacteria

Results: From January 2015 to December 2016, 299 from 2.542 (11.7%) blood culture was positive, with staphylococcus aureus, Enterococcus spp., Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter spp., respectively 5, 6, 24, 5, 20 with total 60 (20%). The MDR and XDR pathogen found respectively 47 and 13 patient.

Conclusion: The prevalence of MDR and XDR pathogens in pediatric patients in Dr. Hasan Sadikin Hospital is not as high as the prevalence reported on other studies worldwide.


Keyword: Antibiotic resistance, Bacterial, Children, MDR, XDR, PDR.